grant

Delineation of the role of RasGRP4 in mast cell growth, differentiation and activation, using RasGRP4 deficient mice [ 2010 - 2012 ]

Also known as: Mast cells and asthma

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/630402]

Researchers: Prof Steven Krilis (Principal investigator)

Brief description Mast cells are important in immunity. Mast cells have been implicated in asthma and more recently they have been shown to participate in immunity against bacteria, viruses and fungi. We have identified a specific protein, RasGRP4, which is restricted to mast cells and plays an important role in their development and function. Understanding this molecule more extensively will give us a much better understanding of diseases that the mast cell is involved in such as asthma and other disorders.

Funding Amount $AUD 636,199.34

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857