Defining the in vivo contribution of leukocyte extracellular traps to infective disease [ 2015 - 2018 ]

Research Grant

Researchers: Prof Graham Lieschke (Principal investigator) ,  Philip Crosier

Brief description Neutrophils are the white blood cells that protect against infection. A surprising protective neutrophil behaviour was recently described – neutrophils can pack up their internal DNA and antimicrobial enzymes and explosively release them into their surrounds, forming a “Neutrophil Extracellular Trap” (NET). This project uses zebrafish built have fluorescent neutrophils to study NET release in living animals. We will learn how NETs control infection and what goes wrong when NETs cause disease.

Funding Amount $AUD 598,363.82

Funding Scheme Project Grants

Notes Standard Project Grant