grant

Defining the stage specific requirements for Bcl-2 family members in the development and maintenance of B cell memory [ 2012 - 2014 ]

Also known as: The molecular mechanism of long-lived B cell memory

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1021374]

Researchers: Dr Ingela Vikstrom (Principal investigator) ,  Dr Simon Willis (Principal investigator)

Brief description Both vaccinations and pathogenic infections provoke an immune response. Our immune system ñmemorizesî this response, enabling a faster and stronger reaction upon re-encounter. This memory requires specialized cells of the immune system, some of which secrete antibodies and some of which patrol the body. Remarkably, these cells can live for decades in humans and provide immunity. In this project we will study the roles of specific proteins regulating the generation and survival of memory cells.

Funding Amount $AUD 632,438.56

Funding Scheme Project Grants

Notes New Investigator Grant

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