Defining the role of kidney CD103+Dendritic cells for treatment of chronic kidney disease [ 2018 - 2020 ]

Research Grant

Researchers: Dr Yiping Wang (Principal investigator) ,  Dr Qi Cao ,  Dr Yuan Min Wang ,  Prof David Harris

Brief description Chronic kidney disease (CKD) is a major cause of death and morbidity. Current treatments for CKD are not effective and new therapeutic approaches are needed. Dendritic cells (DCs) are key immune cells and play a central role in kidney disease. We recently found that a major DC subset called CD103+ DCs harmed the kidney in an animal model of human CKD. This study is to determine how CD103+ DCs cause kidney damage, and how to target CD103+ DCs for development of new therapies for human CKD.

Funding Amount $AUD 607,823.04

Funding Scheme Project Grants

Notes Standard Project Grant