Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1008053]Researchers: Prof Gail Risbridger (Principal investigator)
Brief description Activins are members of the inhibin/TGF_ superfamily of growth and differentiation factors. Our published work implicates one of them, activin-_C as a regulator of activin A synthesis and/or its action. To test our hypothesis we will cross activin-_C over-expressing mice (ActC++ ) with inhibin a subunit knock-out mice (_-KO) that develop gonadal and adrenal tumourigenesis and is caused by increased activin A. We predict that if correct, we will prevent or delay reproductive and adrenal tumourigenesis and prolong survival.
Funding Amount $AUD 441,511.92
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 1008053
- PURL : https://purl.org/au-research/grants/nhmrc/1008053
