grant

Defining the molecular effectors of gene/environment interaction on mouse heart development [ 2012 - 2014 ]

Also known as: The effect of hypoxia on mouse heart formation

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1019776]

Researchers: Prof Sally Dunwoodie (Principal investigator) ,  Dr Duncan Sparrow Prof Stuart Grieve

Brief description One third of all birth defects involve the heart, and are the most common cause of infant death. Some defects are due to genetic factors, but others arise when the pregnant mother is exposed to environmental stress. We will examine how one stress (low oxygen levels) causes abnormal heart formation in the embryo, look at what causes this at a molecular level, and explore if such stress increases the risk of heart defects in families with a history of such abnormalities

Funding Amount $AUD 749,271.82

Funding Scheme Project Grants

Notes Standard Project Grant

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