Defining the genetic and epigenetic targets involved in serrated neoplasia of the colorectum [ 2008 - 2009 ]

Research Grant

Researchers: A/Pr Kevin Spring (Principal investigator) ,  Prof Barbara Leggett ,  Prof Graeme Young

Brief description We believe that some colon cancers develop from a type of polyp called a hyperplastic polyp and that many of these polyps contain a specific mutation in a gene called BRAF. We are conducting tumour studies using mouse models that carry different mutated genes to understand their role and importance in the pathway by which these cancer evolve. Understanding this will allows us to develop better treatments for pateints suffering from colon cancer.

Funding Amount $AUD 324,122.60

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant