grant

Defining the genetic and environmental factors that cause abnormal vertebral segmentation during embryogenesis [ 2010 - 2012 ]

Also known as: Understanding how genes and environment interact in the embryo to affect formation of the spine

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/635500]

Researchers: Prof Sally Dunwoodie (Principal investigator) ,  Dr Duncan Sparrow

Brief description Many birth defects cause vertebral malformations along the spinal column. They originate as the fetus forms, and may be caused by gene mutation or environmental factors. Whilst studying one type of vertebral malformation we have found a genetic cause for 30% of cases. We will investigate the genetic and environmental cause of the remainder. We will look for new genes causing this disease, and use a mouse model to learn how low oxygen levels during pregnancy causes such malformations

Funding Amount $AUD 724,146.99

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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