grant

Deciphering the epigenetic code of T lymphocyte stability in disease [ 2013 - 2016 ]

Also known as: Understanding the epigenetic code of T lymphocyte stability in disease

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1049307]

Researchers: Dr Rhys Allan (Principal investigator) ,  Prof Gabrielle Belz

Brief description T lymphocytes defend against invading pathogens and establish immunological memory to protect us if the infection returns. As there are many different types of pathogens, T lymphocytes must be flexible in the way they respond to infection but also stable once they have decided on the appropriate type of response. This complex decision-making appears to be dictated by epigenetic changes to the chromatin state of the cell. This work will uncover epigenetic factors that maintain this balance to protect us against disease.

Funding Amount $AUD 662,785.20

Funding Scheme Project Grants

Notes Standard Project Grant

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