Data

Data set for "AMPK activators have compound and concentration-specific effects on brain metabolism"

University of New South Wales
Gary Housley (Aggregated by, Principal investigator) Amr Al Abed (Aggregated by) Andre Bongers (Aggregated by) Caroline Rae (Aggregated by) Dominik Fröhlich (Aggregated by)
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.26190/unsworks/24751&rft.title=Data set for AMPK activators have compound and concentration-specific effects on brain metabolism&rft.identifier=https://doi.org/10.26190/unsworks/24751&rft.publisher=UNSW, Sydney&rft.description=Dataset consists of NMR spectra with integrals, plus excel spreadsheets containing calculations and protein concentrations for the experiments described in the manuscript AMPK activators have compound and concentration-specific effects on brain metabolism published in The Journal of Neurochemistry in 2023. The NMR spectra are in Bruker format and are processed with integrals. Each sample has three spectra recorded sequentially; a fully relaxed 1H spectrum, a fully relaxed 13C-decoupled 1H spectrum and a 1H-decoupled 13C NMR spectrum. Control samples (N = 4) are first, followed by 4 samples at EC50 and 4 samples at 10 x EC 50 apart from Metformin which also has an extra 4 intermediate samples. The spreadsheets contain integrals and calculations of values including relaxation compensation factors, protein concentrations and reference to the formate standard at 2 mM.&rft.creator=Gary Housley&rft.date=2023&rft_rights= https://creativecommons.org/licenses/by/4.0/&rft_subject=brain tissue slices&rft_subject=AMPK&rft_subject=NMR Spectra&rft_subject=BIOLOGICAL SCIENCES&rft_subject=HEALTH&rft_subject=EXPANDING KNOWLEDGE&rft.type=dataset&rft.language=English Access the data
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Dataset consists of NMR spectra with integrals, plus excel spreadsheets containing calculations and protein concentrations for the experiments described in the manuscript "AMPK activators have compound and concentration-specific effects on brain metabolism" published in The Journal of Neurochemistry in 2023. The NMR spectra are in Bruker format and are processed with integrals. Each sample has three spectra recorded sequentially; a fully relaxed 1H spectrum, a fully relaxed 13C-decoupled 1H spectrum and a 1H-decoupled 13C NMR spectrum. Control samples (N = 4) are first, followed by 4 samples at EC50 and 4 samples at 10 x EC 50 apart from Metformin which also has an extra 4 intermediate samples. The spreadsheets contain integrals and calculations of values including relaxation compensation factors, protein concentrations and reference to the formate standard at 2 mM.

Issued: 2023

Data time period: 2018-01-01 to 2018-12-30

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Subjects
AMPK | Biological Sciences | Expanding Knowledge | Health | NMR Spectra | brain tissue slices |

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Identifiers
ACN 633 798 857