grant

Cytotoxic T lymphocyte synapse formation and serial killing: When breaking up is hard to do. [ 2014 - 2016 ]

Also known as: How immune cells kill cancer

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1064419]

Researchers: Dr Misty Jenkins (Principal investigator)

Brief description Killer T cells are a specialised group of immune cells, which destroy cancerous and infected cells. When killer T cells find a target, they attach and secrete toxic molecules. It then detaches from the dying target, so that it may go on to kill other cells. If it doesn’t detach properly, it remains bound to the target cell and results in an improper immune response. This proposal will investigate how the killer cell detaches, which is essential for an efficient immune response.

Funding Amount $AUD 626,688.79

Funding Scheme Project Grants

Notes New Investigator Grant

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