grant

Cytolytic mechanisms required for virus elimination. [ 2008 - 2010 ]

Also known as: Understanding the killing of virus infected cells.

Funded by National Health and Medical Research Council
Managed by The Walter and Eliza Hall Institute of Medical Research
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/508905]

Researchers: Dr Justine Mintern (Principal investigator)

Brief description Viruses provoke devastating disease. The immune system kills cells that are infected with viruses. To do this, immune cells release granules that are packaged with different killer molecules. It is unknown which killer molecules participate over the course of an immune response to virus. Here, we will investigate this process for cells that are infected with influenza A virus and herpes simplex virus. This study will allow the design of strategies to limit widespread damage inflicted by viruses.

Funding Amount $AUD 698,567.52

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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Subjects
Biomedical and Clinical Sciences | Clinical Chemistry (Incl. Diagnostics) | Clinical Sciences | NK cells | cell-mediated cytotoxicity | cytotoxic T cells | granzyme | herpes simplex virus | immunity to infection | influenza | vaccine | viral immunity |
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