[Cite as http://purl.org/au-research/grants/nhmrc/570771]
Dr Bernadette Saunders
Prof Georges Grau
Prof Warwick Britton
Brief description Tuberculosis (TB) infects 33% of the world, causing over 2 million deaths per year. TB disease causes damaging lung pathology and new therapies to treat the infection and moderate inflammation are urgently required. TNF is essential for immunity to TB, acting to modulate inflammation. This grant will determine how soluble and membrane- bound TNF regulate the cellular and cytokine control of TB pathology and may lead to new therapies to limit inflammation in TB and other inflammatory diseases.
Funding Amount $AUD 455,899.19
Funding Scheme NHMRC Project Grants
Standard Project Grant