Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/570933]Researchers: Prof Michael Murray (Principal investigator)
Brief description Omega-3 polyunsaturated fatty acids (PUFAs) decrease cancer risk in man whereas omega-6 PUFA, which are common in western diets, increase risk. In cells cytochrome P450 converts PUFAs to epoxides. Omega-6 epoxides stimulate growth of cells and tumours but we have found that epoxides of the omega-3 eicosapentaenoic acid inhibit cell growth. We will now evaluate the mechanisms of these effects, which could lead to new anticancer treatments, perhaps based on altered diet.
Funding Amount $AUD 495,710.84
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 570933
- PURL : https://purl.org/au-research/grants/nhmrc/570933