Curing antibiotic resistance: probiotic plasmids and microbial husbandry in the Enterobacteriaceae [ 2015 - 2018 ]

Research Grant

Researchers: Prof Jonathan Iredell (Principal investigator) ,  A/Pr Sally Partridge ,  Prof Ian Paulsen

Brief description The most troublesome emerging antibiotic resistance is coming in the form of addictive and promiscuous 'pest' plasmids, carrying dangerous genes that defeat antibiotics used for the most severe infections. We currently manage this problem by isolating infected patients and trying to design new antibiotics. Our approach eradicates these plasmids and renders the host bacterium antibiotic susceptible again, thereby restoring the natural ecology in animals and potentially in humans.

Funding Amount $AUD 560,832.54

Funding Scheme Project Grants

Notes Standard Project Grant