grant

Critical Role of Proprotein Convertase 6 in Human Uterine Epithelium for Embryo Implantation and Clinical Implications [ 2010 - 2012 ]

Also known as: Role of PC6 in human uterus for implantation and clinical implications

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/611804]

Researchers: Prof Guiying Nie (Principal investigator) ,  Prof Luk Rombauts

Brief description Implantation of an embryo into the uterus is a key step for human development. Implantation failure causes embryonic death, pregnancy loss and infertility. Conversely, preventing implantation is an attractive approach for contraception. We have established that proprotein convertase 6 (PC6) is a master regulator of implantation. We will investigate how PC6 works in a woman's uterus, and how we can use this knowledge to improve implantation in IVF and to develop PC6 drugs for new contraceptives.

Funding Amount $AUD 643,899.17

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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