grant

Creating Stem Cell Niches to Repair the Nigrostriatal System [ 2008 - 2010 ]

Also known as: Repairing the brain in Parkinsons Disease

Funded by National Health and Medical Research Council
Managed by The University of Melbourne
Managed by University of Melbourne
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/508960]

Researchers: Prof Malcolm Horne (Principal investigator)

Brief description It has been difficult to treat Parkinson's with stem cells because transplants make to few new cells and form tumors. In other organs, specialized locations called niches regulate the division and maturation of stem cells. By making a niche in the brains of animals with experimental parkinsonism we induced the brain to make new nerve cells and repair the parkinsonism. This is important because it shows how to use cell based therapies to treat neurodegenerative disorders. .

Funding Amount $AUD 837,033.62

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Biomedical and Clinical Sciences | Medical Infection Agents (Incl. Prions) | Medical Microbiology | Neuronal Stem Cells | Neuronal proliferation | Parkinson's Disease | Stem Cell Niches | cell therapy | neurodegenerative and age-related diseases | neuronal differentiation | nigrostriatal system |
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