Coupling the cell cortex to membranes: structural basis for the activation and control of ezrin [ 2015 - 2018 ]

Research Grant

Researchers: Prof Paul Curmi (Principal investigator) ,  A/Pr Till Boecking

Brief description Cells are dynamic: they change shape, communicate with each other and import/export signalling molecules. These dynamic processes are controlled via the interaction of the cell membrane with the underlying actin cytoskeleton and they are important for health, for example, they are critical for proper immune cell function. The goal of this project in to unravel the control of membrane dynamics by defining the interactions between the cell membrane and the proteins: ezrin and RhoA.

Funding Amount $AUD 587,548.20

Funding Scheme Project Grants

Notes Standard Project Grant