Correlative structure-function studies of cis- and trans-Golgi membrane traffic in mammalian cells [ 2009 - 2013 ]

Research Grant

Researchers: Dr Brad Marsh (Principal investigator) ,  Prof Brian Storrie

Brief description This project combines imaging by light and electron microscopy with additional techniques for studying protein function at the molecular level, to elucidate how changes in the 3D organisation of cellular machinery can lead to fundamental changes in the function and health of mammalian cells. Although this work includes detailed investigation of the 'insulin factory', it has the potential to modify established concepts on membrane traffic and protein secretion well beyond the field of diabetes.

Funding Amount $AUD 649,531.32

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant