grant

Copper and its antibacterial action: an emerging aspect of host defence against bacterial pathogens [ 2008 - 2011 ]

Also known as: How copper is used by the host to kill bacteria

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/519722]

Researchers: Prof Alastair Mcewan (Principal investigator) ,  Prof Mark Schembri

Brief description This project will determine the way in which copper is used as an antimicrobial agent to kill Salmonella that reside inside the macrophage (white blood cell) of the host and also determine how Salmonella defends against copper-dependent killing. It will also determine the role of copper in the killing of extra-intestinal pathogens during sepsis. These results will provide information that can be used to manage and control infections intracellular and extracellular bacterial pathogens.

Funding Amount $AUD 454,858.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
321010 | Bacterial pathogen | Copper transport | Innate Immunity | Microbial infections | Microbiology - pathogenesis | Nosocomial infections | Salmonella typhimurium | Sepsis | Virulence |
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