Coordination of the Fanconi anemia pathway to maintain genome stability [ 2017 - ]

Research Grant

Researchers: Dr Wayne Crismani (Principal investigator)

Brief description Fanconi anaemia is a heritable disorder where bone marrow failure occurs on average at age seven and is the major cause of death at around age 20. Many patients also develop leukaemia, representing another overwhelming hurdle in their youth. The incorrect function of any one of 19 proteins can lead to Fanconi anaemia. We will search for a drug that can compensate for the absence of one of these proteins to allow correct function of the other proteins offering possible leads for treatment.

Funding Amount $470,144.00

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF