Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1057742]Researchers: Prof David Huang (Principal investigator) , A/Pr Christopher Burns , Dr David Segal
Brief description Cancer cells are often sustained by evading cell death. Thus, a promising approach to develop new cancer treatments aims to restore their ability to commit cell suicide. Proteins related to Bcl-2 are, in this regard, attractive targets because they are prominent barriers to cell death. This project seeks to uncover how a Bcl-2 relative, Mcl-1, is regulated, and to explore how the mechanisms that underpin these processes can be targeted in cancers (melanomas, leukemias) that it sustains.
Funding Amount $AUD 749,414.99
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1057742
- PURL : https://purl.org/au-research/grants/nhmrc/1057742