The control and regulatory mechanisms of artemisinin induced dormancy in P. falciparum [ 2012 - 2015 ]

Research Grant

Researchers: Dr Qin Cheng (Principal investigator) ,  A/Pr Norman Waters ,  Dr Marina Chavchich ,  Dr Michelle Gatton ,  Dr Nanhua Chen

Brief description Malaria is a major global health problem and can only be reliably treated with artemisinin combinations in many areas due to widespread of drug resistance. However a proportion of parasites appear to be able to avoid the lethal effects of the drug by becoming “dormant” following exposure. They resume growth after the drug is wanned, a feature which is reminisent to cell cycle arrest. This study investigates the role of cell cycle machinery in dormancy following arteminsinin treatment.

Funding Amount $AUD 495,552.85

Funding Scheme Project Grants

Notes Standard Project Grant