Control of the Ras/Erk signaling pathway by the Brahma chromatin-remodeling complex [ 2011 - 2013 ]

Research Grant

Researchers: Dr Boris Sarcevic (Principal investigator) ,  A/Pr Helena Richardson

Brief description Hormones bind and initiate molecular signals within cells to proliferate or change into specific cell types. This is important for growth and development of different tissues. A pathway which is critical for transmitting the effects of hormones in cells is the Ras pathway. New studies by the applicants indicate that the Brahma complex, a molecule important in controlling the levels of proteins in cells, activates the Ras pathway. This project will define how Brahma controls the Ras pathway.

Funding Amount $AUD 524,820.33

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant