Control of insulin secretion by Y1 receptor signalling [ 2018 - 2020 ]

Research Grant

Researchers: Dr Yanchuan Shi (Principal investigator) ,  A/Pr David Laybutt ,  Prof Herbert Herzog

Brief description Diabetes is the most common metabolic disease worldwide. Impaired insulin secretion and beta cell function is one of its major causes. We have recently discovered a key signaling pathway that we believe hold the secret to inhibiting insulin secretion in beta cells and blocking it leads to significant insulin release. This proposal focuses on this pathway and its regulation using innovative and unique tools. This will provide a novel treatment option for diabetes as well as islet transplantation.

Funding Amount $AUD 685,040.16

Funding Scheme Project Grants

Notes Standard Project Grant