Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/509325]Researchers: Dr Belinda Parker (Principal investigator) , A/Pr Matthew Bogyo , Prof Robin Anderson
Brief description Breast cancer is a serious clinical problem once the disease spreads to distant tissues such as lung and bone. We have identified a group of genes called the cysteine cathepsin proteases that have increased activity in breast cancers that spread to bone and we have shown this in a mouse model and also in human cancer. We will investigate the contribution of these genes to invasion and test whether inhibiting specific cathepsins can prevent spread of breast cancer to bone in our mouse model .
Funding Amount $AUD 447,094.34
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 509325
- PURL : https://purl.org/au-research/grants/nhmrc/509325
