A comprehensive analysis of the role of the Alcohol Dehydrogenase gene cluster in alcohol-related disorders and esophageal cancer through deep resequencing [ 2014 - 2017 ]

Research Grant

Researchers: Dr Penelope Lind (Principal investigator) ,  Dr Allan Mcrae ,  Dr John Whitfield

Brief description Excessive alcohol consumption remains a major public health concern in Australia where the burden of mental health disorders is dominated by substance-use disorders. Alcohol dehydrogenases (ADHs) are essential in the breakdown of alcohol in the body and we seek to resequence seven ADH genes with the aim to comprehensively catalogue and identify sequence variants that contribute to risk for consuming excessive quantities of alcohol, alcoholism and esophageal squamous cell carcinoma.

Funding Amount $AUD 605,323.85

Funding Scheme Project Grants

Notes Standard Project Grant