grant

Complement activation in experimental epilepsy: role of C5a receptors [ 2010 - 2012 ]

Also known as: How epilepsy develops and how it can be prevented

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/631451]

Researchers: Dr Karin Borges (Principal investigator) ,  Prof Stephen Taylor

Brief description 400,000 patients in Australia suffer from epilepsy and 45% of them suffer from uncontrolled seizures. Epilepsy often develops after head injury or stroke, but no treatments are available to prevent this process. Inflammatory processes seem to be involved in epilepsy. We will investigate if the inflammatory complement factor C5a plays a role in epilepsy and if we can prevent development of seizures in mice. If successful our data will be a prerequisite for later clinical trials.

Funding Amount $AUD 314,716.75

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857