Competition for polarity influences lymphocyte differentiation and function [ 2008 - 2012 ]

Research Grant

Researchers: Dr Jane Oliaro (Principal investigator)

Brief description CD46 is a protein on human cells that viruses and bacteria bind to during infection. Our laboratory has found that binding of CD46 on immune cells impairs their ability to recognize and kill target cells and may explain the immunosuppression caused by measles infection. We aim to investigate the mechanisms behind the effect of CD46 on immune cells. The outcomes of this study will define new paradigms in lymphocyte biology and determine how CD46 influences the immune response to infection.

Funding Amount $AUD 380,558.72

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF