A comparative study of the pathophysiology of severe knowlesi and falciparum malaria [ 2013 - 2015 ]

Research Grant

Researchers: A/Pr Tsin Yeo (Principal investigator) ,  Prof Nicholas Anstey (Principal investigator) ,  Dr Timothy William ,  Prof Arjen Dondorp

Brief description Plasmodium knowlesi causes monkey malaria, but has recently been found to infect humans resulting in severe disease and death similar to Plasmodium falciparum. Clinical features of severe P. knowlesi and how it causes complications are poorly described and understanding this could improve treatment and outcomes. In patients with P. knowlesi, we want to describe the clinical features, the ability to cause severe disease, and measure 1) markers of platelet activation and 2) capillary obstruction and red cell deformability,

Funding Amount $AUD 660,293.75

Funding Scheme Project Grants

Notes Standard Project Grant