A Comparative Clinical Efficacy Trial of Treatments for Melancholia [ 2010 - 2013 ]

Research Grant

Researchers: Prof Gordon Parker (Principal investigator) ,  A/Pr Vijaya Manicavasagar ,  Mr Dusan Hadzi-Pavlovic

Brief description This study seeks to improve treatment of melancholic depression by comparing three treatments, i) a selective serotonin reuptake inhibitor (SSRI), ii) cognitive behaviour therapy (CBT) and, iii) a broad-spectrum antidepressant sequencing treatment approach. We hypothesize that the latter will be superior to both i) SSRI monotherapy, and ii) CBT monotherapy, over a 12-week trial period. Comparisons will be made with the US-based Sequenced Treatment Alternatives to Relieve Depression trial.

Funding Amount $AUD 309,711.75

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant