grant

Common Fragile Site Genes: Function and Contribution to Cancer Cell Biology [ 2008 - 2011 ]

Also known as: How the genes spanning specified sites of DNA instability in human cells can contribute to cancer

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/519125]

Researchers: Prof Robert Richards (Principal investigator) ,  Dr Louise O'Keefe

Brief description Common fragile sites are regions on human chromosomes that everybody has. These regions are much more sensitive to damage from agents in the environment (including the diet) than other regions in human chromosomes - so when damage does occur it is more likely to occur at these fragile sites. Many of the most sensitive fragile sites have large genes that span them. We need to understand the function of these genes to see how their disruption can contribute to cancer.

Funding Amount $AUD 474,597.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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