Combined T cell checkpoint blockade to eradicate established cancer [ 2014 - 2016 ]

Research Grant

Researchers: A/Pr Michele Teng (Principal investigator)

Brief description We will use combinations of antibodies to rescue exhausted immune effector T cells in cancers or deplete those T cells that suppress tumor immunity. These exciting new approaches have potential curative impact for the treatment of many human cancers. The mouse has been a useful predictive model and in mice, we will aim to study the combinatorial efficacy and mechanism of action of the most promising antibodies and design a new and more specific means to deplete intratumor regulatory T cells.

Funding Amount $AUD 207,588.69

Funding Scheme Project Grants

Notes Standard Project Grant