Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/351556]Researchers: Prof Robert Tindle (Principal investigator) , Dr Carsten Wiethe
Brief description Vaccines to prevent or treat infectious diseases and some cancers are urgently needed. Infected cells and some cancer cells display unique proteins which the body's immune system can recognises as 'foreign'. The body will then mount an immune response, which, if successful, will eradicate the infected or cancerous cells. Dendritic cells (DCs) initiate the body's immune response by instructing other immune cells to mount a response. For a vaccine to be successful it is important that the vaccine activates the DCs in the right way. We propose to activate DCs by vaccinating with DNA encoding recently identified costimulatory molecules, as well as DNA encoding the foreign antigen. Our earlier work leads us to believe that this will enhance the immune response, and lead to a more effective state of immunity
Funding Amount $AUD 182,000.00
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 351556
- PURL : https://purl.org/au-research/grants/nhmrc/351556
