A Cluster Randomised Controlled Trial of Selective Decontamination of the Digestive Tract in Critically Ill Patients [ 2015 - 2019 ]

Research Grant

Researchers: A/Pr Ian Seppelt (Principal investigator) ,  A/Pr Joshua Davis ,  Dr Colman Taylor ,  Prof Andrea Marshall ,  Prof John Myburgh
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Brief description Sepsis is the most common cause of death in intensive care patients. Selective Decontamination of the Digestive Tract (SDD) is a treatment to reduce the risk of infection and improve survival for these patients. Many trials suggest SDD works but there has not been widespread uptake due to concerns that SDD will increase antibiotic resistance.rates. This trial will provide a definitive answer. If SDD reduces mortality without increasing antibiotic resistance, the study will have a global impact.

Funding Amount $AUD 4,113,393.72

Funding Scheme Project Grants

Notes Standard Project Grant