Clonal Evolution in Myelodysplasia and Acute Myeloid Leukaemia following Azacitidine [ 2017 - 2020 ]

Research Grant

Researchers: Prof Mark Dawson (Principal investigator) ,  A/Pr Sarah-Jane Dawson

Brief description The myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) represent a spectrum of clinically heterogeneous malignancies that remain incurable in the vast majority of patients. Whilst the DNA mutations underpinning the initiation/maintenance of these malignancies are largely known we have little insight into how these mutations alter response to therapy. Using a range of sophisticated cutting edge technologies we will study how these DNA mutations evolve over the course of treatment.

Funding Amount $AUD 875,061.27

Funding Scheme Project Grants

Notes Standard Project Grant