Clinical utility and cost-effectiveness of genome sequencing for refractory epilepsy in children and adults: a multicentre randomised controlled trial [ 2018 - ]

Research Grant

Researchers: Prof Patrick Kwan (Principal investigator) ,  Dr Saul Mullen ,  Dr Slavé Petrovski ,  Prof Ingrid Winship ,  Prof Julie Ratcliffe

Brief description A large number of genomic variants have been found to underpin common types of epilepsy and to predict adverse drug reactions. However, the adoption of genomic testing in the routine management of epilepsy is hampered by uncertainties around its clinical utility and cost-effectiveness. This randomised controlled trial aims to determine the diagnostic efficiency, clinical and psychosocial impact, and cost-effectiveness of whole genome sequencing for refractory epilepsy in children and adults.

Funding Amount $720,609.00

Funding Scheme Project Grants

Notes Standard Project Grant