Do ‘classical’ or ‘oxidative’ UVR-induced DNA adducts drive melanoma induction after ultraviolet radiation [ 2013 - 2015 ]

Research Grant

Researchers: Dr Graeme Walker (Principal investigator) ,  E/Pr H Muller

Brief description There is debate about the mechanisms by which sun exposure influences melanoma development. This leads to difficulties in formulating adequate sunscreens and guidelines for safe levels of exposure. We will elucidate the critical UV-induced DNA adducts that are necessary for MM development. This will introduce experimental evidence into the debate about sun exposure and melanoma. The use of post sunburn creams containing enzymes which rapidly remove the dangerous DNA adducts will be indicated.

Funding Amount $AUD 335,757.70

Funding Scheme Project Grants

Notes Standard Project Grant