Clarifying molecular role of IGF-1:Ea isoforms in skeletal muscle hypertrophy and atrophy [ 2009 - 2011 ]

Research Grant

Researchers: A/Pr Thea Shavlakadze (Principal investigator) ,  Prof Miranda Grounds (Principal investigator) ,  Dr Christopher Mcmahon

Brief description The growth factor IGF-1 is proposed as a therapeutic agent to increase muscle mass and to reduce muscle wasting resulting from denervation, disuse, ageing and dystrophy. Understanding the precise mechanisms of IGF-1 action is essential for the potential therapeutic use of this factor. This research is focused on the molecular role of IGF-1 in healthy muscle and in the conditions of muscle wasting and degeneration.

Funding Amount $AUD 394,718.35

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant