Clamp stabilized vaccines to provide broad spectrum protection against influenza [ 2019 - ]

Research Grant

Researchers: Prof Paul Young (Principal investigator) ,  Dr Daniel Watterson ,  Dr Keith Chappell ,  Prof Patrick Reading

Brief description Protection against disease provided by current influenza vaccines is limited by narrow virus strain specificity. We developed a novel ‘molecular clamp’ technology that constrains the major viral immune target into its native structure. Immunization results in immune responses with increased virus killing and improvements in cross-reactivity and protection against divergent viruses. Our approach will be further developed and compared to current commercial vaccines.

Funding Amount $949,516.00

Funding Scheme Development Grants

Notes Development Grant