Circuit Breaker: Investigating the regulatory circuits controlling expression of drug efflux pumps in the nosocomial pathogen Acinetobacter baumannii [ 2017 - 2019 ]

Research Grant

Researchers: Prof Ian Paulsen (Principal investigator) ,  Dr Karl Hassan

Brief description Hospital-acquired infections caused by drug resistant pathogenic bacteria cost billions of dollars and increase patient pain and morbidity. This research will study the genes controlling multidrug efflux pumps in a major hospital-acquired bacterial pathogen, Acinetobacter baumannii. These efflux pumps make the bacteria resistant to antimicrobials by pumping them out of the cell. The results will allow us to better track drug resistant strains and will inform treatment options.

Funding Amount $AUD 527,809.21

Funding Scheme Project Grants

Notes Standard Project Grant