grant

Chronic bacterial infection and the generation of T cell memory: implication for vaccination against tuberculosis [ 2009 - 2012 ]

Also known as: Chronic bacterial infection and T cell memory

Funded by National Health and Medical Research Council
Managed by The University of Sydney
Managed by University of Sydney
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/570768]

Researchers: A/Pr James Triccas (Principal investigator) ,  Prof Warwick Britton

Brief description Two million people die from tuberculosis (TB) each year. The immune system is unable to eradicate the TB bacterium, and the type of immune response needed to protect against the disease is poorly understood. We will use animal models of TB infection and sophisticated immunological techniques to decipher how the TB bacterium interacts with the immune sytem and causes disease. We will also develop new TB vaccines that aim to boost the immune response in the lung, the main site of TB infection.

Funding Amount $AUD 547,970.74

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Allergy | Biomedical and Clinical Sciences | Dendritic cells | Immune response | Immunology | Mycobacterial infection | Tuberculosis | Vaccine development | disease model, animals | immunity to infection | improvement of vaccine efficacy |
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