grant

Chronic active viral persistence versus host immune mediated pathology: an analysis and manipulation of the balance. [ 2011 - 2013 ]

Also known as: Understanding the host factors that limit clearance of chronic viruses

Funded by National Health and Medical Research Council
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1006592]

Researchers: Prof Marc Pellegrini (Principal investigator)

Brief description Our robust ability to mount an immune response and clear infections is tempered by the possibility of promoting autoimmunity. Several host genes regulate immunity. Viruses like HIV have exploited these to abrogate antiviral immunity. This project attempts to define host factors that promote chronic infection. This will be extremely valuable in understanding the vulnerabilities of our immune system and provide an insight into how we can treat chronic infections.

Funding Amount $AUD 418,658.10

Funding Scheme Project Grants

Notes New Investigator Grant

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Subjects
Medical and Health Sciences | Medical Microbiology | Medical Virology | T cells | chronic infection | cytokines | hepatitis B infection | hepatitis C virus | human immunodeficiency virus (HIV) | virus pathogenesis |
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