Chromatin regulation of neural stem cell multipotency [ 2015 - 2017 ]

Research Grant

Researchers: A/Pr Anne Voss (Principal investigator) ,  A/Pr Tim Thomas

Brief description The genetic material is packaged in the cell nucleus with histone proteins. Chemical modifications of histones determine if a particular area of the genome is active or repressed. We are investigating a family of histone modifying proteins, the MYST proteins. Mutations in these proteins cause intellectual disability and cancer. In this project we examine the role of MYST2 in brain stem cells. Knowledge gained may become the basis for the development of drugs to treat neurodegenerative disease.

Funding Amount $AUD 756,142.33

Funding Scheme Project Grants

Notes Standard Project Grant