How chromatin compaction is regulated and its link with disease [ 2011 - 2014 ]

Research Grant

Researchers: Prof David Tremethick (Principal investigator) ,  The Australian National University (Managed by)

Brief description Chromosomes are constructed from very small particles called nucleosomes. How these nucleosomes interact with each other to build an entire chromosome is not known but elucidating this mechanism is critical in order to understand cancer when chromosomes become unstable. Furthermore, the strength of nucleosome-nucleosome interactions determines whether a gene is expressed or not. This study will elucidate the nature and the mechanism of how nucleosome-nucleosome interactions are regulated.

Funding Amount $AUD 493,747.86

Funding Scheme Project Grants

Notes Standard Project Grant