grant

Characterization of a novel secretion system necessary for Porphyromonas gingivalis virulence. [ 2008 - 2010 ]

Also known as: Characterization of a novel bacterial secretion system.

Funded by National Health and Medical Research Council
Managed by The University of Melbourne
Managed by University of Melbourne
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/509326]

Researchers: Prof Eric Reynolds (Principal investigator) ,  Prof Stuart Dashper

Brief description In this study we will characterize a novel bacterial secretion system that we have discovered. This sytem mediates the secretion of proteins from the bacterial cell and their attachment to the cell surface. This system is essential for the virulence of Porphyromonas gingivalis, a bacterium associated with chronic periodontitis. The chacterization of this system may offer opportunities for the development of new treatments to target this disease.

Funding Amount $AUD 596,412.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Biomedical and Clinical Sciences | Bacterial secretion system | Chronic inflammation | Medical Physiology | Medical Physiology Not Elsewhere Classified | Oral health | Oral microbiology | Periodontal disease | Porphyromonas gingivalis | Proteinase | Virulence traits |
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