Characterising the pro-inflammatory role of IL-36?/IL-36R in pathogen-induced exacerbations of asthma and COPD [ 2017 - 2020 ]

Research Grant

Researchers: Prof Paul Foster (Principal investigator)

Brief description Lung infections cause exacerbations in patients with asthma and COPD and these are difficult to treat and can be life-threatening. We have discovered that the cytokine pathway, IL-36?/IL-36R, is linked to the host response to bacterial and viral infections that induce exacerbations in these patients. Our studies will provide new insight into the role IL-36?/IL-36R in infection, disease exacerbation and determine the therapeutic benefit of blocking this pathway.

Funding Amount $AUD 757,260.35

Funding Scheme Project Grants

Notes Standard Project Grant