grant

Characterising a novel toxin regulatory mechanism from the new hypervirulent Streptococcal pyogenes M1uk lineage in Australia

Also known as: Ideas Grants

Funded by National Health and Medical Research Council
Managed by University of Wollongong
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/2019767]

Funding Amount $1,058,650.97

Full description Group A Streptococcus (GAS) is a strictly human pathogen that ranks among the top 10 infectious disease killers. A new variant of GAS expressing a novel set of bacterial toxins has emerged in the United Kingdom, known as M1UK. The M1UK lineage is associated with increases in invasive disease. We have now detected that this new GAS M1UK lineage has arrived in Australia. This proposal will define the disease mechanisms underlying this new health threat to Australian and global health.

Chief Investigator Assoc Prof Martina Sanderson-Smith

Date Announced 2022-12-14T00:00:00

Sector University

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Spatial Coverage And Location

text: NSW

Subjects
Basic Science Research | Medical and Health Sciences | Medical Microbiology | Medical Bacteriology | bacterial pathogenesis | bacterial toxins | bacterial virulence factors | biomedical and clinical sciences | group a streptococcal disease | streptococcus pyogenes |
Identifiers
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ACN 633 798 857