Characterising the mutations, signatures, potential new therapeutic targets and biomarkers in malignant mesothelioma using whole genome analysis. [ 2015 - 2018 ]

Research Grant

Researchers: Dr Nicola Waddell (Principal investigator) ,  Mr John Pearson ,  Prof Bruce Robinson ,  Prof Jenette Creaney ,  Prof Sean Grimmond

Brief description Malignant mesothelioma is an aggressive tumour that occurs principally in the pleura as a consequence of inhaling asbestos fibres. Currently there is no cure for malignant mesothelioma. Thus new therapeutic approaches are desperately needed. Such new approaches will require a detailed understanding of the genetic lesions of malignant mesothelioma. Therefore we will perform whole genome sequencing of a large cohort of malignant mesothelioma patients to identify mesothelioma-related alterations.

Funding Amount $AUD 1,219,288.61

Funding Scheme Project Grants

Notes Standard Project Grant