grant

Characterising the molecular pathogenesis of newly emergent invasive group A Streptococcus M4 serotypes in Australia [ 2012 - 2015 ]

Also known as: Characterising newly emerged strains of flesh-eating bacteria in Australia

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1033258]

Researchers: Dr Jason Cole (Principal investigator)

Brief description Group A Streptococcus (GAS) is a human pathogen of global significance, responsible for life-threatening invasive infections such as flesh-eating disease (>650,000 cases per year), with a mortality rate of 25%. A recent outbreak of serotype M4 GAS caused severe invasive infections in Queensland Australia. The aim of this work is to determine how M4 GAS causes invasive disease. Understanding this mechanism will allow the development of new generation therapeutics, treatments and improved health outcomes.

Funding Amount $AUD 523,756.14

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Medical and Health Sciences | Medical Microbiology | Medical Microbiology Not Elsewhere Classified | Streptococcus pyogenes | bacterial pathogenesis | group A streptococcal disease | host/pathogen interaction | infectious diseases | innate immunity | necrotising fasciitis | streptococcal disease | streptococcal infection | streptococcal invasive diseases |
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